Saturday, July 29, 2017

BACTERIOPHAGES: SMALL THINGS CONSIDERED

Bacteriophages ("phages", for short) are viruses that infect prokaryotes (bacteria and archaea), harnessing the resources of the host cell to replicate vast numbers of themselves, eventually causing the cell to lyse and release the phage progeny, which then find new hosts and repeat the cycle. But that's just the textbook definition. What really hooks us in that some phages look just like lunar landers sent from alien spaceships. Merry Youle, one of STC's very own, has written a charming paean to her beloved subjects, a full length book all about "what makes the phages so fascinating, so intriguing, and so important."

Youle tells us, "This book was born of love, exasperation, and wonderment." Youle holds that phages are deserving of far more ink, and respect, than they've thus far received. They exist everywhere where their hosts thrive, including hydrothermal vents, acidic springs, the arctic tundra, and your own gut. They impact geothermal cycles, algal booms, and biodiversity. They are useful tools for genetic manipulation in the lab as well as in nature. and can serve as allies in treating bacterial infections.

Enterobacteriophage T4

http://schaechter.asmblog.org/schaechter/2017/07/a-star-studded-phantastic-voyage-of-phages.html

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